Xiaoshan Zhu
Professor- Phone: (775) 682-6298
- Email: xzhu@unr.edu
- Building:
- Room: 337A
- Mailstop: 0260
- Website:
- Ph.D., Electrical Engineering, University of Cincinnati
- M.S., Electrical Engineering, Tsinghua University, China
- B.S., Electronics Science, Nankai University, China
- B. Sreenan, B. Lee, L. Wan, R. Zeng, J. Zhao, Xiaoshan Zhu*, Review of Development of Mn Doped Nanocrystals for Time-Resolved Luminescence Biosensing/Imaging, ACS Applied Nano Materials, 2022. DOI: 10.1021/acsanm.2c04337.
- Y. Chen, R. Zeng, Q. Wei, S. Zhang, Y. Wang, C. Chen, Xiaoshan Zhu, S. Cao, B. Zou, J. Zhang, Competing-Energy-Transfer Modulated Dual Emission in Mn2+-Doped Cs2NaTbCl6 Rare-Earth Double Perovskites, Journal of Physical Chemistry Letters, 2022, 13, 8529-8536. DOI: 10.1021/acs.jpclett.2c02491.
- T. Chang, Q. Wei, Z. Wang, Y. Gao, B. Lian, Xiaoshan Zhu, S. Cao, J. Zhao, B. Zou, R. Zeng, Phase-Selective Solution Synthesis of Cd-Based Perovskite Derivatives and Their Structure/Emission Modulation, Journal of Physical Chemistry Letters, 2022, 13, 3682–3690, DOI: 10.1021/acs.jpclett.2c00863.
- B. Lee, S. Tian, G. Xiong, Y. Yang, Xiaoshan Zhu*, Solvothermal Synthesis of Transition-metal (Fe/Cu) and Nitrogen Co-Doped Carbon Nanomaterials: Comparing Their Peroxidase-like Properties, Journal of Nanoparticle Research, 2022, 24:85, DOI:10.1007/s11051-022-05470-y.
- B. Lee, T. Hegseth, Xiaoshan Zhu*, Optical Properties of Mn Doped CuGa(In)S-ZnS Nanocrystals (NCs): Effects of Host NC and Mn Concentration, Nanomaterials, 2022, 12, 6: 994, DOI:10.3390/nano12060994.
- T. Hegseth, B. Lee, D. Aucoin, Xiaoshan Zhu*, A Compact and Sensitive Time-Resolved-Optical-Reader for Bioassay Using Low-Energy Excitable and Long-Lived-Fluorescence Nanolabels, IEEE Sensors Letters, 2022, 6, 4, 5000304, DOI:10.1109/LSENS.2022.3159761.
- B. Lee, T. Hegseth, Y. Song, J. Zhao, Xiaoshan Zhu*, Mn-Doped AgZnInS/ZnS Nanocrystals (NCs): Effects of Zn Etching on the NC Optical Properties, Optical Materials, 2022, 123, 111941. DOI:10.1016/j.optmat.2021.111941.
- V. G. Demillo, Xiaoshan Zhu*, Composites and Compositions for Therapeutic Use and Methods of Making and Using The Same, US Patent No. US 10,994,031, B2, May 4, 2021. (83 Pages)
- B. Gallian, M. Saber Zaeimian, D. Hau, D. AuCoin, Xiaoshan Zhu*, A Highly Sensitive Time-Gated Fluorescence Immunoassay Platform Using Mn Doped AgZnInS/ZnS Nanocrystals as Signal Transducers, Frontiers in Physics: Optics and Photonics (Modern Tools for Time-Resolved Luminescence Biosensing and Imaging), 2021, 8:625424, DOI: 10.3389/fphy.2020.625424. (Invited)
- M. Saber Zaeimian, D. AuCoin, Xiaoshan. Zhu*, Immunoassay Using Dendritic Au-Pt Nanoparticles as Signal Labels for Detection of the Biomarker of Burkholderia Pseudomallei, Journal of Nanoparticle Research, 2020, 22:323, DOI: 10.1007/s11051-020-05054-8.
- C. Harrison, B. Gallian, G. Dong, Y. Wang, J. Zhao, Xiaoshan Zhu*, Mn Doped Cu-Zn-In-S/ZnS Nanocrystals: Optical Properties and Their Use as Time-Gated Fluorescence Probes, Journal of Nanoparticle Research, 2019, 21:248, DOI: 10.1007/s11051-019-4666-3.
- B. Gallian, G. Dong, Xiaoshan Zhu*, A Compact Time-Gated Instrument for QDs with Low Excitation Energy and Millisecond Fluorescence Lifetime as Signal Reporters, and Its Detection Application, Review of Scientific Instruments, 2019, 90, 104701, DOI: 10.1063/1.5111147.
- M. S. Zaeimian, B. Gallian, C. Harrison, Y. Wang, J. Zhao, Xiaoshan Zhu*, Mn Doped AZIS/ZnS Nanocrystals (NCs): Effects of Ag and Mn on NC Optical Properties, Journal of Alloys and Compounds, 2018, 765, 236-244.
- S. Chen, M. S. Zaeimian, J. Monteiro, J. Zhao, A. G. Mamalis, A. de Bettencourt-Dias, Xiaoshan Zhu*, Mn Doped AIZS/ZnS Nanocrystals: Synthesis and Optical Properties, Journal of Alloys and Compounds, 2017, 725, 1077-1083.
- Xiaoshan Zhu*, Low Cost, Efficient Dual Signal Amplification for Bioassays, US Patent No. US 9,482,616, B2, Nov 1, 2016. (53 Pages)
- S. Chen, V. G. Demillo, M. Lu, Xiaoshan Zhu*, Preparation of Photoluminescence Tunable Cu-doped AgInS2 and AgInS2/ZnS Nanocrystals and Their Application as Cellular Imaging Probes, RSC Advances, 2016, 6, 51161-51170.
- S. Chen, M. Ahmadiantehrani, J. Zhao, S. Zhu, A. G. Mamalis, Xiaoshan Zhu*, Heat-up Synthesis of Ag-In-S and Ag-In-S/ZnS Nanocrystals: Effect of Indium Precursors on Their Optical Properties, Journal of Alloys and Compounds, 2016, 665, 137–143.
- V. G. Demillo, Xiaoshan Zhu*, Zwitterionic Amphiphile Coated Magnetofluorescent Nanoparticles – Synthesis, Characterization and Tumor Cell Targeting, Journal of Materials Chemistry B, 2015, 3, 8328-8336.
- Z. Xiao, Xiaoshan Zhu, On-Chip Sensing of Thermoelectric Thin Film’s Merit, Sensors, 2015, 2015, 15, 17232-17240. (invited)
- R. Shrake, V. G. Demillo, M. Ahmadiantehrani, N. G. Publicover, K. W. Hunter Jr., Xiaoshan Zhu*, Facilitated Preparation of Bioconjugatable Zwitterionic Quantum Dots Using Dual-Lipid Encapsulation, Journal of Colloid and Interface Science. 2015, 437, 140–146.
- S. Chen, M. Ahmadiantehrani, N. G. Publicover, K. W. Hunter Jr., Xiaoshan Zhu*, Thermal Decomposition Based Synthesis of Ag-In-S/ZnS Quantum Dots and Their Chlorotoxin-Modified Micelles for Brain Tumor Cell Targeting, RSC Advances, 2015, 5, 60612-60620.
- V.G. Demillo, M. Liao, D. Redelman, N. G. Publicover, K. W. Hunter Jr, Xiaoshan Zhu*, Fabrication of MnFe2O4-CuInS2/ZnS Magnetofluorescent Nanocomposites and Their Characterization, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2015, 464, 134–142.
- L. Huang, M. Liao, S. Chen, V. G. Demillo, S. A. Dupre, N. G. Publicover, K. W. Hunter Jr., Xiaoshan Zhu*, A Polymer Encapsulation Approach to Prepare Zwitterion-like, Biocompatible Quantum Dots with Wide pH and Ionic Stability, Journal of Nanoparticle Research, 16, 2555-2564, 2014.
- L. Huang, N. G. Publicover, K. W. Hunter Jr., M. Ahmadiantehrani, A. de Bettencourt-Dias, T. W. Bell, Xiaoshan Zhu*, Cadmium and Zinc Alloyed Cu-In-S Nanocrystals and Their Optical Properties, Journal of Nanoparticle Research, 15, 2056-2066, 2013.
- C. Cowles, Xiaoshan Zhu*, MicroRNA Detection Using Magnetic Separation and Zinc-Based Nanolabels as Signal Transducers, Analytical Methods, 5, 801-804, 2013.
- C. Cowles, Xiaoshan Zhu*, Dual Signal Amplification for Bioassays Using Ion Release of Nanolabels and Ion-Activated Enzyme Kinetics, Analyst, 137, 4815 – 4821, 2012.
- C. Li, F. Pei, Xiaoshan Zhu, D. Duan, C. Zeng, Circulating MicroRNAs as Novel and Sensitive Biomarkers of Acute Myocardial Infarction, Clinical Biochemistry, 45, 727-732, 2012.
- C. Cowles, B. Chen, Xiaoshan Zhu*, Facile Synthesis and Biosensing Application of Hybrid Zinc Nanoparticles, Journal of Nanoscience and Nanotechnology, 12, 4546–4552, 2012.
- C. Cowles, Xiaoshan Zhu*, Sensitive Detection of Cardiac Biomarker Using ZnS Nanoparticles as Novel Signal Transducers, Biosensors and Bioelectronics, 30, 342-346, 2011.
- C. Cowles, C. Pai, Xiaoshan Zhu*, Using Fluorescence Measurement of Zinc Ions Liberated from ZnS Nanoparticle Labels in Bioassay for Escherichia coli O157:H7, Journal of Nanoparticle Research, 13, 5407-5413, 2011.
- C. Cowles, N. Publicover, Xiaoshan Zhu*, Fluorescence Signal Transduction Mechanism for Immunoassay Based on Zinc Ion Release from ZnS Nanocrystals, Analyst, 136, 2975 – 2980, 2011.
- Xiaoshan Zhu*, Bead-Based Optical Immunoassay Using Quantum-Dot Labeling and Immunocomplex Dissociation for Detection of Escherichia coli O157:H7, Analytical Letters, 44, 874-884, 2011.
- Xiaoshan Zhu*, D. Duan, S. Madsen, N. Publicover, Compatibility of Quantum Dots with Immunobuffers, and its Effect on Signal/Background of Quantum Dot-based Immunoassay, Analytical and Bioanalytical Chemistry, 369, 1345-1353, 2010.
- Xiaoshan Zhu*, D. Duan, N. Publicover, Magnetic Bead Based Assay for C-Reactive Protein Using Quantum-Dot Fluorescence Labeling and Immunoaffinity Separation, Analyst, 135, 381-389, 2010.
- Xiaoshan Zhu*, Micro/Nanoporous Membrane Based Gas-Water Separation in Microchannel, Microsystem Technologies, 15, 1459-1465, 2009.
- A. Bange, J. Tu, Xiaoshan Zhu, C. Ahn, B. Halsall, W. Heineman, Electrochemical Detection of MS2 Phage Using a Bead-based Immunoassay and a NanoIDA, Electroanalysis, 19, 2202-2207, 2007.
- Xiaoshan Zhu, and C. H. Ahn, On-chip Electrochemical Analysis System Using Nanoelectrodes and Bioelectronic CMOS Chip, IEEE Sensors Journal, 5, 1280- 1286, 2006. (cover page article)
- Xiaoshan Zhu, and C. H. Ahn, Electrochemical Determination of Reversible Redox Species at Interdigitated Array Micro/Nanoelectrodes Using Charge Injection Method, IEEE Transaction on NanoBioscience, 4, 164-169, 2005.
- Xiaoshan Zhu, C. Gao, J. W. Choi, P. L. Bishop and C. H. Ahn, On-Chip Generated Mercury Microelectrode for Heavy Metal Ion Detection, Lab Chip, 5, 212-217, 2005.
- Xiaoshan Zhu, J. W. Choi, and C. H. Ahn, A New Dynamic Electrochemical Transduction Mechanism for Interdigitated Array Microelectrodes, Lab Chip, 4, 581 – 587, 2004.
Research interests
- New chemical/physical properties of nanomaterials and their applications in bio-detection
- Multi-modality bioimaging using engineered composite nanomaterials for disease diagnosis and therapy
- Integrated sensor systems using bioMEMS technologies
- Development, evaluation, and application of biosensors for environmental analysis, food safety, medicine, etc.