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Summary

Dr. Krause earned a Bachelor of Science in Biology at Sonoma State University in 2007. He did his senior thesis with Dr. Daniel E. Crocker investigating the hormonal regulation of sodium balance in lactating and fasting elephant seals. In 2008, Dr. Krause joined the laboratory of John C. Wingfield at the University of California, Davis, and focused on the endocrine regulation of stress and reproduction in songbirds. After completing his Ph.D. he continued as a postdoctoral researcher in the laboratory of Dr. John C. Wingfield for one year until a collaborative grant with Dr. Simone L. Meddle, at the Roslin Institute, University of Edinburgh, was funded in 2016. Between 2016 and 2018, Dr. Krause split his time between the University of California, Davis, and the Roslin Institute studying seasonal changes in gene expression associated with stress and reproduction. Dr. Krause was hired by the University of ÁùºÏ±¦µä, Reno, Biology Department, in 2018 as a teaching assistant professor. Dr. Krause enjoys teaching using the dry erase board. He remains active in research and has several ongoing collaborations.

Research interests

Dr. Krause is classically trained as a physiologist although his interests have broadened over his career to include ecology and behavior. He is particularly interested in how organisms integrate environmental information to control the expression and progression through life history stages (ie migration, breeding, molt, etc). As an endocrinologist, he is particularly interested in how physiology and behavior are controlled through endocrine signaling mechanisms. Dr. Krause's research focused on the regulation of stress and reproduction in White-crowned sparrow (Zonotrichia leucophrys) and Lapland longspurs (Calcarius lapponicus). Birds, as with many other species across a broad range of taxa, use the endocrine system to appropriately time reproduction while dealing with environmental challenges (predation, storms, food shortages, etc). The importance of the interplay between these two systems is becoming more evident as animals deal with a changing environment either through climate change or encroachment by urbanization. Seasonally breeding animals are under a strong selective pressure to breed at the appropriate time of year to ensure high fecundity. This has resulted in selection and utilization of key environmental signals, such as photoperiod, to control endocrine signaling cascades for various physiological processes including reproduction. However, environmental stressors can impair the reproductive axis through the secretion of the stress hormone corticosterone. Dr. Krause's research has focused on the regulation of stress and reproduction by investigating plasma levels of hormone and tissue expression of receptors and steroid metabolizing enzymes.

Dr. Krause has joined a team of arctic biologists to work on a newly funded National Science Foundation (NSF) grant which provided support for the Evolving Meta-Ecosystems Institute. The institute will be investigating how biological systems interact over space and time in response to rapidly changing climates in the Alaskan Arctic.

Courses taught

• BIOL 316 (Comparative Animal Physiology)
• BIOL 396 (Comparative Animal Physiology Laboratory)
• BIOL 414 (Endocrinology)
• BIOL 452 (Comparative Behavioral Endocrinology)

Education

• Postdoctoral Research, Roslin Institute, University of Edinburgh Scotland and University of California Davis, 2016-2018
• Postdoctoral Research, University of California Davis, 2015-2016
• Ph.D. in Molecular, Cellular and Integrative Physiology, University of California Davis, 2014
• B.S. in Biology with emphasis in Physiology, Sonoma State University, 2007
• A.A., Santa Rosa Junior College, 2005

Selected publications

• Rhodes M, Yap K.N., Mesquita P.H.C., Parry H.A., Kavazis A.N., Krause J.S., Hill G.E., Hood W.R. Flexibility underlies differences in mitochondrial function in migratory and non-migratory White-crowned Sparrows (Zonotrichia leucophrys) 2024 14 (1), 9456.
• Ramenofsky M., Campion A.*, Hwee D.T., Krause J.S., Nemeth Z. & Bodine S. Phenotypic flexibility of migrant and resident white-crowned sparrows during Spring and Autumn Seasons. Ecological and Evolutionary Physiology. 2024 97 (1), 11-28.
• Wu Z., Miedzinska, Krause J.S., Perez J.H., Wingfield J.C., Meddle S.L., Smith J. A Chromosome level genome assembly of free living-white-crowned sparrow. Scientific Data. 2024, 11 (1), 86.
• Gonzalez-Gomez, P., Villavicencio C.P., Quispe R., Schwabl P., Cornelius J., Ramenofsky M., Krause J.S., and J.C. Wingfield. Perspectives on environmental heterogeneity and seasonal modulation of stress response in neotropical birds. 2023, 152, 105359.
• Snell K.R.S, Young R., Krause J.S., Collinson M., Wingfield J.C., & Thorup K. Integrating orientation mechanisms, adrenocorticoid activity and endurance flight in vagrancy behavior. Scientific Reports, 2022, 12 (1), 22104.
• Heppner J., Krause J.S. & Ouyang J. Urbanization and maternal hormone transfer: Endocrine and morphological phenotypes across ontogenetic stages. General and Comparative Endocrinology, 2023, 333, 114166.
• Boardman L., Julie L. Lockwood J.L., Angilletta M.J., Krause J.S., Lau J.A., Loik M.E., Simberloff D., Thawley C.J., & Meyerson L.A. The future of invasion science needs physiology, Bioscience, 2022, 72 (12), 1204-1219
• Krause J.S., Watkins T*., Reid A.M.A., Pérez J.H., Cheah J.C. *, Wingfield J.C., Ramenofsky M., & Meddle S.L. Gene expression of sex steroid metabolizing enzymes and receptors in the skeletal muscle of migrant and resident subspecies of white-crowned sparrow (Zonotrichia leucophrys). Oecologia 2022, 199: 549–562
• Names G., Schultz E., Krause J.S., Hahn T.P., Wingfield J.C., Heal M., Klasing K.C., and Hunt K.E. Stress in paradise: effects of elevated corticosterone on immunity and avian malaria resilience in a Hawaiian passerine Journal of Experimental Biology, 2021, 224 (20), jeb242951.
• Austin S., Krause J.S, Viernes R., Lee C., Farrar V.S., Bond A., Booth A.M., Wingfield J.C., MacManes M.M., and Calisi R.M. Uncovering the Sex-specific Endocrine Responses to Reproduction and Parental Care. Frontiers in Endocrinology, 2021, 12, 120
• Pérez J.H., Krause J.S., Reid A.M.A., Wingfield J.C., & Meddle S.L. Seasonal differences in hypothalamic thyroid stimulating hormone β (TSHβ), gonadotropin-releasing hormone-I and deiodinase expression between migrant and resident subspecies of white-crowned sparrow (Zonotrichia leucophrys). Journal of Neuroendocrinology, 2021, 33 (9), e13032
• Names G., Krause J.S., Schultz E., Angelier F., Parenteau C., Ribout C., Wingfield J.C. Stress in paradise: relationships between avian malaria resilience and three immunomodulatory hormones in the endemic Hawaii Amakihi (Chlorodrepanis virens), 2021, General and Comparative Endocrinology, 308: 113784.
• Austin S.H., Harris R., Booth A.M., Lang A., Farrar V.S., Krause J.S, Hallman T., MacManes M.M., and Calisi R.M. Isolating the role of corticosterone in the hypothalamic-pituitary-gonadal genomic response to acute stress, 2021, Frontiers in Endocrinology 12, 120.
• Krause J.S., Pérez J.H., Reid A.M.A., Cheah J.C.*, Wingfield J.C., & Meddle S.L. Acute restraint stress does not alter corticosteroid receptor or 11β-Hydroxysteroid dehydrogenase gene expression at Hypothalamic-Pituitary-Adrenal axis regulatory sites in captive male white-crowned sparrows (Zonotrichia leucophrys gambelii). General and Comparative Endocrinology, 2021, 303: 113701
• Krause J.S., Nemeth Z., Lau H.J*, Swanson R.E. *, Cheah J.C. *, Pérez J.H., Meddle S.L., Wingfield J.C., & Ramenofsky M. Annual regulation of adrenocortical function in migrant and resident subspecies of white-crowned sparrow. 2021, Hormones and Behavior 127: 104884.

* indicates undergraduate coauthors